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MSI.EAGLE -- Fly Ions Fly: Tools for High-Throughput Analysis of Mass Spectrometry Imaging Data
March 29, 2023 | 6:00 PM EDT (In-person meeting)
at the Waters Corporation
5205 Militia Hill Rd, Suite #100 Plymouth Meeting, PA 19462
Refreshments will be provided. With speaker Dr. Aalim Weljie from the University of Pennsylvania
Please RSVP to Noelle_Elliott@waters.com
Workshop: RAMP in the Research Lab (virtual)
Thursday, April 13, 2023 | 3:00 PM 6:00 PM EDT
via Zoom
This 3-hour workshop is for frontline researchers in academic institutions: graduate students, postdoctoral scholars, and undergraduate students. It will introduce the principles of the RAMP paradigm (recognize hazards, assess risk, minimize risk, and prepare for emergencies), through a series of case studies and discussion sessions focused on practicing each of the RAMP steps. By the end, attendees will have learned and practiced how to systematically do a risk assessment of existing protocols as well as for past incidents.
The workshop is $25 per attendee, and participants will receive a certificate of participation to add to their resume or portfolio upon completion of the workshop.
Register by Wednesday, March 29, 2023!
2022 Carothers Award
“There and Back Again: Therapies for the Treatment of
Obesity and Diabetes”
Dr. Ann E. Weber (Kallyope Inc.)
Tuesday, April 18, 2023
DuPont Country Club, Wilmington, DE
- Reception 5:30-6:30 pm
- Served dinner 6:30 pm
Choice of Pan-seared Chicken Breast with Roasted Mushrooms and Lemon Caper Pan Sauce (or) Vegetarian Lasagna Roulades - Award presentation and address 7:30 pm
Register by March 7th.
If you are sitting at a sponsor table, do not use the below link to register. Contact awards chair Andrea Martin at aemartin1@widener.edu.
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Abstract:
The incidence of obesity continues grow world-wide, and according to the World Health Organization, at least 2.8 million people die each year from co-morbidities associated with being overweight or obese, including cardiovascular disease and diabetes. My own work to address metabolic disorders began at Merck over 30 years ago with the development of agonists for the beta3 adrenergic receptor, a target that ultimately failed in obesity, but later proved highly effective in the treatment of overactive bladder (OAB). This work led to GEMTESA® (vibregron), which was approved by the FDA in 2020 for the treatment of patients with OAB. The demise of the obesity program in 2000 provided the opportunity to initiate a new medicinal chemistry effort on dipeptidyl peptidase IV (DPP-4) inhibitors for the treatment of patients with type 2 diabetes. This research, which spanned over 10 years, led to two marketed products, JANUVIA® (sitagliptin) and MARIZEV® (omarigliptin). More recently, moving from big pharma to the biotech Kallyope has allowed me to take a fundamentally new approach to the treatment of diseases including obesity by targeting the gut-brain axis. This talk will feature vignettes from all these efforts.
Biography: Ann E. Weber, Ph.D., is Senior Vice President – Research & Development at Kallyope Inc., a New York City-based biotechnology company focused on harnessing the potential of the gut and gut-brain axis to improve human health. In this part-time role, she is responsible for activities that support the company’s R&D efforts. She joined Kallyope in October 2016 as Head of Drug Discovery and served as Head of Preclinical Development from January 2020 – February 2023. She was formerly Vice President – Lead Optimization Chemistry at Merck Research Laboratories (MRL), responsible for the discovery of innovative therapeutic agents across disease areas. She joined MRL as a Senior Research Chemist in 1987.
Dr. Weber’s research interests include the design and synthesis of ligands for G-protein coupled receptors, ion channels and enzymes. Her work has led to several marketed medications including JANUVIA® (sitagliptin), a treatment for patients with Type 2 diabetes. She is the author or co-author of over 90 publications and co-inventor on over 35 issued US patents. Her awards include the Heroes of Chemistry Award (ACS), the Gift of Mentoring Award from the Metro Women Chemists Committee, and the Perkin Medal (Society of Chemical Industry American Section).
Dr. Weber is passionate about advancing women in science and is a past member of the ACS Women Chemists Committee. She also serves on the University of Notre Dame College of Science Advisory Council and Berthiaume Institute for Precision Health Advisory Board. Before joining Merck, Dr. Weber obtained her B.S. degree in chemistry summa cum laude from the University of Notre Dame. She earned her PhD degree from Harvard University, studying synthetic organic chemistry in the laboratories of Professor David A. Evans.
EVENT CALENDAR
PAST EVENTS
2022 Delaware Section Award Banquet
Dr. Stephen McCann, FMC Crop Protection
Tuesday, March 14, 2023
Empowering Academic Researchers to Strengthen Safety Culture
2 PM to 5:30 PM ET
DE ACS Children's Chemistry Adventure
At The Independence School
1300 Paper Mill Road, Newark, DE 19711
Saturday, December 10, 12-3 PM
Polymers for Medical Applications
2-Day Live Virtual Short Course, Presented by Dr. Subbu Venkatraman, Innovations Manager, UC San Diego
November 2 & 4, 2022
Delaware Section Election
Submission deadline 10/26/2022
2021 Carothers Award Presentation and Address
October 11, 2022
2021 DELAWARE SECTION AWARD ADDRESS
Keynote Speaker – Dr. Donald Watson, University of Delaware
September 13, 2022
MARM 2022: Our Chemical Revolution
Middle Atlantic Regional Meeting
June 1-4, 2022
DELAWARE CHEMISTRY CONFERENCE & AWARD CEREMONY
Keynote Speaker – Dr. Sarah Wengryniuk
May 20, 2022
U.S. National Chemistry Olympiad (USNCO) for Delaware
April 27, 2022
Delaware Section Award Address
Fifty Years of Organofluorine Chemistry
April 26, 2022
ACS Delaware Section Participated in the Catalyzing Change
STEM Talent Conference
April 13, 2022
2022 College Student
Award Winners
Ishika Govil
University of Delaware
Department of Chemical Engineering
Michael Axiotes
University of Delaware
Department of Chemistry & Biochemistry
Angelica Paneda
Delaware State University
Chemistry Major
Chia-Chun Chen
2022 Blunt Scholarship Winner
Delaware Technical Community College